Ethyl bromopyruvate → Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylate

HRID 2107262Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2107262
[C:1]1([CH3:11])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8]([NH2:10])=[S:9].Br[CH2:13][C:14](=O)[C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[C:1]1([CH3:11])[C:2]([NH:7][C:8]2[S:9][CH:13]=[C:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

3

Edukt 2

HCID 66144Ethyl bromopyruvateHCID 2787703N-(2-Methylphenyl)thiourea

Produkt 1

HCID 1284666Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylate

Versuchsvorschrift

Following a procedure similar to that described in Preparation 42, the desired compound was prepared from 20 g of o-tolylthiourea, 23 g of ethyl bromopyruvate and 200 ml of giving the desired compound as pale yellow prismatic crystals having the following physical properties.

Aufarbeitung

  1. customthat described in Preparation 42

Quellen und Nachweise

ORD-Eintrag
ord-da3135c3ccd34c7e8119818b079f7594
Quelldatensatz
uspto-grants-1990_06
Patentnummer
US04933355

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