4-Bromo-2-thiophenecarboxylic Acid → N-(3-Methoxybenzyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamide
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:24]=[CH:25][CH:26]=1)[CH2:6][NH:7][C:8]([C:10]1[CH:14]=[C:13]([C:15]2[C:23]3[C:18](=[N:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)SC=1)=[O:9].BrC1C=[C:30](C(O)=O)[S:31]C=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:24]=[CH:25][CH:26]=1)[CH2:6][NH:7][C:8]([C:10]1[S:31][CH:30]=[C:13]([C:15]2[C:23]3[C:18](=[N:19][CH:20]=[CH:21][CH:22]=3)[NH:17][CH:16]=2)[CH:14]=1)=[O:9]Komponenten
3
Versuchsvorschrift
The above compound was made by the same procedure as N-(3-methoxybenzyl)-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-3-carboxamide starting with the regioisomer, 4-bromothiophene-2-carboxylic acid.
Quellen und Nachweise
- ORD-Eintrag
- ord-da59599092b64a03bd5870bf4dcd0bed
- Quelldatensatz
- uspto-grants-2009_04
- DOI