Benzenesulfonyl chloride → HCID 131727395, Verbindung
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]([C:12]1[C:13](C2C=CC=CC=2CN)=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:11].[C:26]1(S(Cl)(=O)=O)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1.N1C=CC=CC=1CCNC(C1C(C2C=CC=CC=2[CH2:59][NH:60][S:61]([C:64]2[CH:69]=[CH:68][CH:67]=[CH:66][CH:65]=2)(=[O:63])=[O:62])=CC=CC=1)=O>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]([C:12]1[C:13]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[CH:14][CH:15]=[CH:16][C:17]=1[CH2:59][NH:60][S:61]([C:64]1[CH:65]=[CH:66][CH:67]=[CH:68][CH:69]=1)(=[O:62])=[O:63])=[O:11]Komponenten
4
Versuchsvorschrift
From 0.3 mmol of 2′-aminomethylbiphenyl-2-carboxylic acid 2-(2-pyridyl)-ethylamide (precursor 5d) and phenylsulfonyl chloride, according to the general working procedure 117 mg of 2′-(phenylsulfonylaminomethyl)-biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide were obtained;
Aufarbeitung
- customwere obtained