Potassium Hydroxide → 3-(2-Oxoimidazolidin-1-yl)benzonitrile
Reaktionsgleichung
Cl[CH2:2][CH2:3][NH:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14]#[N:15])[CH:9]=1)=[O:6].[OH-].[K+]>C(O)C>[O:6]=[C:5]1[NH:4][CH2:3][CH2:2][N:7]1[C:8]1[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=1)[C:14]#[N:15]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
110.00 g (490 mmol) 1-(2-chloro-ethyl)-3-(3-cyano-phenyl)-urea are dissolved in 2000 ml of ethanol at 50° C. and a solution of 42.00 g (640 mmol) potassium hydroxide in 390 ml of ethanol is added within 1.5 hours. The reaction mixture is stirred for 16 hours at ambient temperature, then the precipitate formed is suction filtered, washed with water and dried.
Aufarbeitung
- customthe precipitate formed
- filtrationfiltered
- washwashed with water
- customdried
Quellen und Nachweise
- ORD-Eintrag
- ord-feabf3cb4bfc46c88916fe5dbfd4b2e7
- Quelldatensatz
- uspto-grants-2009_04
- Patentnummer
- US07517995B2
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