HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethyl Ether → 1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethyl Ether | HCID 3283 | — |
| Edukt | 5-(3-Chlorophenyl)furfural | HCID 609822 | — |
| Edukt | HCID 178418689 | HCID 178418689 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 1-[5-(3-Chlorophenyl)-2-furyl]ethan-1-ol | HCID 62498593 | — |
Reaktionsschritte
To a solution of 5-(3-chlorophenyl)furan-2-carbaldehyde (1.0 equiv.) in THF at 0° C. was added MeMgBr in ether (3.0 equiv.) and stirred for 45 min. The reaction was quenched with water, diluted with ether and filtered through Celite. The organic layer was separated and washed with brine, dried over MgSO4, and concentrated to give the 1-[5-(3-chlorophenyl)-2-furyl]ethan-1-ol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07521062B2 |
| Quelldatensatz | uspto-grants-2009_04 |
| ORD ID | ord-91b98511bff74a6a8e5fcf415860793e |
| Quellennotiz | uspto-grants-2009_04 |