5-Amino-2-oxindole → 2-Oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-acetamide

Beteiligte Stoffe

Reaktionsschritte

The title compound is prepared from oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid and 5-amino-1,3-dihydro-indol-2-one according to the method described in Example 2. The filtered crystals are purified by column chromatography using Kieselgel 60 (Merck) as adsorbent and toluene:methanol=4:1 as eluent. Melting Point: 176-178° C. (diethyl ether)

Herkunft & Nachweise