Azido(trimethyl)stannane → HCID 178522024, Verbindung
Reaktionsgleichung
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:26])[C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([C:24]#[N:25])[CH:19]=2)=[O:16])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:27]([Sn](C)(C)C)=[N+:28]=[N-:29]>C1(C)C=CC=CC=1>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:26])[C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([C:24]3[NH:29][N:28]=[N:27][N:25]=3)[CH:19]=2)=[O:16])[CH2:12][CH2:13]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 0.7 g (2 mmol) of 2-(4-benzyl-piperidin-1-yl)-N-(3-cyanophenyl)-2-oxo-acetamide, 0.82 g (4 mmol) of azidotrimethyltin (Aldrich) and 20 ml of toluene is refluxed for 20 hours. The precipitated crystals are filtered off and treated with 20 ml of N hydrochloric acid to yield 0.42 g (54%) of the title compound. Melting Point: 159-161° C. (water)