6-amino-3,4-dihydroquinolin-2(1H)-one → 6-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-ethylamino}-3,4-dihydro-1H-quinolin-2-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	6-amino-3,4-dihydroquinolin-2(1H)-one	HCID 4912759	—
Edukt	2-Chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone	HCID 69100056	—
Lösungsmittel	Ethanol	HCID 702	—
Produkt	6-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-ethylamino}-3,4-dihydro-1H-quinolin-2-one	HCID 69100682	—

Reaktionsschritte

The title compound is prepared from 6-amino-3,4-dihydro-quinolin-2-one and 2-chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone (Example 197a) according to the method described in Example 206. Melting Point: 197-200° C. (ethyl alcohol)

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07435744B2
Quelldatensatz	uspto-grants-2008_10
ORD ID	ord-cca28e7feefb476988880f7bfe4e83d5
Quellennotiz	uspto-grants-2008_10