2-Amino-6-chlorobenzaldehyde → (+/-)-(2-Amino-6-chlorophenyl)-cyclopentyl-methanol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Amino-6-chlorobenzaldehyde	HCID 22399512	—
Edukt	HCID 178419650	HCID 178419650	—
Lösungsmittel	Ethyl Acetate	HCID 8857	—
Produkt	(+/-)-(2-Amino-6-chlorophenyl)-cyclopentyl-methanol	HCID 69315836	36%

Reaktionsschritte

This compound was prepared using General Method 1 (EXAMPLE 1) from 2-amino-6-chlorobenzaldehyde (0.30 g, 1.9 mmol) and cyclopentylmagnesium bromide (2 M in ether, 1.9 mL)) to afford 0.16 g (36%) of (±)-(2-amino-6-chlorophenyl)-cyclopentyl-methanol after flash chromatography (4:1 hexanes:ethyl acetate).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07442696B2
Quelldatensatz	uspto-grants-2008_10
ORD ID	ord-ada438d7963c4adbb6c39fe67aac7a39
Quellennotiz	uspto-grants-2008_10