Ammonia → N-(3-Amino-2-oxoazetidin-3-yl)-2-phenoxyacetamide
Reaktionsgleichung
CS([C:4]1([NH:9][C:10](=[O:19])[CH2:11][O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:7][NH:6][C:5]1=[O:8])=O.[NH3:20]>O1CCCC1>[NH2:20][C:4]1([NH:9][C:10](=[O:19])[CH2:11][O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:7][NH:6][C:5]1=[O:8]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The sulphoxide (26) (186 mg) in dry tetrahydrofuran (6 ml) was treated with dry ammonia gas (14.8 ml) and the mixture stirred at room temperature for 3 days. The solvent was evaporated and the residue chromatographed on silica gel to give the product, (27) (113 mg).
Aufarbeitung
- customThe solvent was evaporated
- customthe residue chromatographed on silica gel
Quellen und Nachweise
- ORD-Eintrag
- ord-575c2014c86a456c95df2053e717e5b5
- Quelldatensatz
- uspto-grants-1987_07
- Patentnummer
- US04678782
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