HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-Amino-4-vinylisoindolinone → 7-Amino-4-ethylisoindolinone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 7-Amino-4-vinylisoindolinone | HCID 68488659 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 7-Amino-4-ethylisoindolinone | HCID 68490969 | 102,8% |
Reaktionsschritte
7-Amino-4-vinylisoindolinone (50.0 mg, 0.287 mmol) was dissolved in DMF (2.5 mL), and the solution was added with 10% Pd—C (10 mg) followed by stirring at room temperature for 1.8 hours under normal pressure and hydrogen atmosphere. The reaction mixture was filtered using Celite and the solvent of the filtrate was evaporated under reduced pressure to obtain 7-amino-4-ethylisoindolinone (52.0 mg, quantitative).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07745641B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-9b574fe409a9418d963834a7bf341de1 |
| Quellennotiz | uspto-grants-2010_06 |