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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 21187Erstellt: 23. Oktober 2026

7-Amino-4-vinylisoindolinone → 7-Amino-4-ethylisoindolinone

https://huagongshe.com/de/reaction/21187

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt7-Amino-4-vinylisoindolinoneHCID 68488659—
EduktHCID 178418361HCID 178418361—
KatalysatorPalladiumHCID 23938—
LösungsmittelDimethylformamideHCID 6228—
Produkt7-Amino-4-ethylisoindolinoneHCID 68490969102,8%

Reaktionsschritte

7-Amino-4-vinylisoindolinone (50.0 mg, 0.287 mmol) was dissolved in DMF (2.5 mL), and the solution was added with 10% Pd—C (10 mg) followed by stirring at room temperature for 1.8 hours under normal pressure and hydrogen atmosphere. The reaction mixture was filtered using Celite and the solvent of the filtrate was evaporated under reduced pressure to obtain 7-amino-4-ethylisoindolinone (52.0 mg, quantitative).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07745641B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-9b574fe409a9418d963834a7bf341de1
Quellennotizuspto-grants-2010_06