HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Salicylaldehyde → 3-(2-Hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Salicylaldehyde | HCID 6998 | — |
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | 6-Thiophen-3-yl-1,3-dihydroindol-2-one | HCID 23439027 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 3-(2-Hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one | HCID 53674365 | 69% |
Reaktionsschritte
A mixture of 6-thiophen-3-yl-1,3-dihydroindol-2-one (100 mg, 0.5 mmol), 2-hyroxy-benzaldehyde (60 mg, 0.5 mmol) and piperidine (0.23 mL) in ethanol (4 mL) was stirred at reflux overnight. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 110 mg (69%) of 3-(2-hydroxybenzylidene)-6-thiophen-3-yl-1,3-dihydroindol-2-one as yellow-red crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06689806B1 |
| Quelldatensatz | uspto-grants-2004_02 |
| ORD ID | ord-810dfb8b26d54e3086376f582cc18ff8 |
| Quellennotiz | uspto-grants-2004_02 |