4-Nitrophenol → 2-Propanol, 1,3-bis(p-nitrophenoxy)-

HRID 2120321Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2120321
[CH:1]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][CH:4]=[C:3]([OH:10])[CH:2]=1>C1(C)C(C)=CC=CC=1>[N+:7]([C:6]1[CH:5]=[CH:4][C:3]([O:10][CH2:2][CH:3]([OH:10])[CH2:4][O:10][C:3]2[CH:4]=[CH:5][C:6]([N+:7]([O-:9])=[O:8])=[CH:1][CH:2]=2)=[CH:2][CH:1]=1)([O-:9])=[O:8]

Komponenten

3

Edukt 1

HCID 9804-Nitrophenol

Produkt 1

HCID 4590272-Propanol, 1,3-bis(p-nitrophenoxy)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel

Versuchsvorschrift

76.5 g (0.55 mole) of p-nitrophenol, 32.3 g (0.25 mole) of glycerol-αα′-dichlorohydrin, and 500 ml of xylene were added to a reaction solution, and the reaction mixtures were heated with stirring under a nitrogen current. After dissolving the solid, 345 g (2.5 moles) of potassium carbonate anhydride was added, and the reaction mixtures were refluxed with stirring for 12 hours. The reacted solution was separated by filtration while it was warm. After cooling, hexane was added to the filtrate. A yellow viscous liquid was obtained. After column purification and drying this liquid, a 55 g-yellow viscous liquid (1,3-bis (4-nitrophenoxy)-2-propyl alcohol) was obtained.

Aufarbeitung

  1. customthe reaction mixtures
  2. temperaturewere heated
  3. additionwas added
  4. customthe reaction mixtures
  5. temperaturewere refluxed
  6. stirringwith stirring for 12 hours
  7. customThe reacted solution was separated by filtration while it
  8. temperaturewas warm
  9. temperatureAfter cooling
  10. additionhexane was added to the filtrate
  11. customA yellow viscous liquid was obtained
  12. customAfter column purification
  13. customdrying this liquid

Quellen und Nachweise

ORD-Eintrag
ord-3a093f462d024b53bfa3715945a97110
Quelldatensatz
uspto-grants-2004_02
Patentnummer
US06689899B2

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