2-(Methylsulfonyl)-5-(trifluoromethyl)pyrimidine → 2-[1-(3,4-dimethoxy-benzyl)-6-methoxy-7-(5-trifluoromethyl-pyrimidin-2-yloxy)-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide

Reaktionsgleichung

[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:20][C:21](=[O:22])[NH:23][CH:24]3[CH2:25][CH2:26][c:27]4[cH:28][cH:29][cH:30][cH:31][c:32]43)[CH2:9][CH2:10][c:11]3[cH:12][c:13]([O:18][CH3:19])[c:14]([OH:17])[cH:15][c:16]32)[cH:33][cH:34][c:35]1[O:36][CH3:37].[CH3:38][S:39](=[O:40])(=[O:41])[c:42]1[n:43][cH:44][c:45]([C:48]([F:49])([F:50])[F:51])[cH:46][n:47]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:20][C:21](=[O:22])[NH:23][CH:24]3[CH2:25][CH2:26][c:27]4[cH:28][cH:29][cH:30][cH:31][c:32]43)[CH2:9][CH2:10][c:11]3[cH:12][c:13]([O:18][CH3:19])[c:14]([O:17][c:42]4[n:43][cH:44][c:45]([C:48]([F:49])([F:50])[F:51])[cH:46][n:47]4)[cH:15][c:16]32)[cH:33][cH:34][c:35]1[O:36][CH3:37]