2-[[4-[5-(4-fluorophenyl)pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-N-hydroxy-3-methylbutanamide → 2-[[4-[5-(3,4-dichlorophenyl)pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-N-hydroxy-3-methylbutanamide

Reaktionsgleichung

[Cl:32][c:33]1[cH:34][c:35](-[c:40]2[cH:41][n:42][c:43]([N:46]3[CH2:47][CH2:48][N:49]([S:52](=[O:53])(=[O:54])[CH2:55][CH:56]([C:57](=[O:58])[OH:59])[CH:60]([CH3:61])[CH3:62])[CH2:50][CH2:51]3)[n:44][cH:45]2)[cH:36][cH:37][c:38]1[Cl:39].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:6]2[cH:7][n:8][c:9]([N:10]3[CH2:11][CH2:12][N:13]([S:14]([CH2:15][CH:16]([CH:17]([CH3:18])[CH3:19])[C:20](=[O:21])[NH:27][OH:28])(=[O:22])=[O:23])[CH2:24][CH2:25]3)[n:26][cH:29]2)[cH:30][cH:31]1>>[NH:27]([OH:28])[C:57]([CH:56]([CH2:55][S:52]([N:49]1[CH2:48][CH2:47][N:46]([c:43]2[n:42][cH:41][c:40](-[c:35]3[cH:34][c:33]([Cl:32])[c:38]([Cl:39])[cH:37][cH:36]3)[cH:45][n:44]2)[CH2:51][CH2:50]1)(=[O:53])=[O:54])[CH:60]([CH3:61])[CH3:62])=[O:58]