Dichloromethane → Piperazine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dichloromethane	HCID 6344	—
Edukt	N-[3-chloro-phenyl]-4-[2-(1-piperazinyl)-4-pyridyl]-2-pyrimidineamine	HCID 21948237	—
Lösungsmittel	Methanol	HCID 887	—
Produkt	Piperazine	HCID 4837	—
Produkt	N-(3-chlorophenyl)-4-(2-chloropyridin-4-yl)pyrimidin-2-amine	HCID 9905031	—

Reaktionsschritte

Analogously to Example 1, there is obtained from 100 mg (0.31 mmol) of N-[3-chloro-phenyl]-4-(2-chloro-4-pyridyl)-2-pyrimidineamine and 500 mg (5.63 mmol) of piperazine, from the melt after chromatography (methylene chloride:methanol=95:5), N-[3-chloro-phenyl]-4-[2-(1-piperazinyl)-4-pyridyl]-2-pyrimidineamine;

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05728708
Quelldatensatz	uspto-grants-1998_03
ORD ID	ord-8b8f64beacb447798a17fed01f8b02fc
Quellennotiz	uspto-grants-1998_03