Acetonitrile → HCID 68668375, Verbindung

HRID 216314

Reaktionsgleichung

Reaktionsgleichung von HRID 216314
F[B-](F)(F)F.[N:6]#[O+:7].[CH3:8][C:9]([CH3:15])([CH2:13][CH3:14])[CH2:10][CH:11]=[CH2:12].[C:16](#[N:18])[CH3:17]>>[CH3:8][C:9]([CH3:15])([CH2:13][CH3:14])[CH2:10][C:11]1[N:18]=[C:16]([CH3:17])[N:6]([OH:7])[CH:12]=1

Komponenten

4

Edukt 3

HCID 6342AcetonitrileHCID 1371364,4-Dimethyl-1-hexeneHCID 11137142Nitrilooxonium tetrafluoroborate

Produkt 1

HCID 68668375HCID 68668375, Verbindung

Versuchsvorschrift

Nitrosonium tetrafluoroborate 45 g (0.38 mol) was added in three portions to a 0° C. solution of 4,4-dimethyl-1-hexene (43 g, 0.38 mol) in acetonitrile (100 mL). After stirring at ambient temperature for 1 h, the reaction mixture was filtered and the filtrate was concentrated in vacuo. The residue was dissolved in ethyl acetate and washed with water, saturated aqueous sodium bicarbonate and brine, dried (magnesium sulfate), filtered and concentrated in vacuo to afford 4-(2,2-dimethylbutyl)-2-methyl-1H-imidazol-1-ol which was used in the subsequent step without further purification.

Aufarbeitung

  1. filtrationthe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated in vacuo
  3. dissolutionThe residue was dissolved in ethyl acetate
  4. washwashed with water, saturated aqueous sodium bicarbonate and brine
  5. dry with materialdried (magnesium sulfate)
  6. filtrationfiltered
  7. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-e8e4cbd842094a0cb5f370941b023fc7
Quelldatensatz
uspto-grants-2012_06
Patentnummer
US08193228B2

Verknüpfte Notizen

Wird geladen…