N-(4-amino-2-chlorophenyl)pentanamide → HCID 20981468, Verbindung

HRID 2163226

Reaktionsgleichung

Reaktionsgleichung von HRID 2163226
N[C:2]1[CH:14]=[CH:13][C:5](NC(=O)CCCC)=[C:4](Cl)[CH:3]=1>N1C=CC=CC=1>[CH3:4][CH2:3][CH:2]=[CH:14][CH2:3][CH2:4][CH2:5][CH2:13][CH:14]=[CH2:2]

Komponenten

3

Edukt 1

HCID 4257591N-(4-amino-2-chlorophenyl)pentanamide

Produkt 1

HCID 20981468HCID 20981468, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

A mixture of 4'-amino-2'-chlorovaleranilide (2.27 g., 0.01 mole) anti-tricyclo[4.2.2.02,5 ]dec-3,9-diene-endo7,endo-8-dicarboxylic anhydride (2.02 g., 0.01 mole) and pyridine (20 ml.) is heated under reflux for twenty-four hours. The solvent is removed in vacuo and the residue (4.35 g., m.p. 120°-136° C.) is recrystallized from butyl chloride to give N-(3-chloro-4-valeramidophenyl)-antitricyclo[4.2.2.02,5 ]dec-3,9-diene-endo-7,endo-8-dicarboximide, m.p. 157.5°-159° C.

Aufarbeitung

  1. temperatureis heated
  2. temperatureunder reflux for twenty-four hours
  3. customThe solvent is removed in vacuo
  4. customthe residue (4.35 g., m.p. 120°-136° C.) is recrystallized from butyl chloride

Quellen und Nachweise

ORD-Eintrag
ord-a9a2f288ba2a4b6a87a79791d48284ac
Quelldatensatz
uspto-grants-1979_01
Patentnummer
US04132799

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