Pinacolone → HCID 86735615, Verbindung
Reaktionsgleichung
CC(C(C)(C)C)=O.[C:8]([C:12]([CH:14]=[O:15])=O)([CH3:11])([CH3:10])[CH3:9].CC(=[N:19][OH:20])C>>[C:8]([C:12](=[N:19][OH:20])[CH:14]=[O:15])([CH3:11])([CH3:10])[CH3:9]Komponenten
4
Versuchsvorschrift
Yet another oxime intermediate is prepared from t-butyl methyl ketone, which is first transformed into t-butylglyoxal using the procedure of Fuson et al., J. Am. Chem. Soc. 61, 1938 (1939). The t-butylglyoxal, in aqueous solution at pH 4-5, is allowed to react with acetone oxime (commercially available) at about room temperature for about two days. The reaction product mixture is worked up by extracting it with ether, and the t-butylglyoxal oxime is isolated from the ether extract as colorless needles having a melting point of about 50-52° C.