Acetohydrazide → HCID 12207321, Verbindung

HRID 2163475Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2163475
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[N:9]=[C:10]=[S:11].[C:12]([NH:15][NH2:16])(=[O:14])[CH3:13]>C1COCC1>[C:12]([NH:15][NH:16][C:10]([NH:9][C:3]1[CH:4]=[C:5]([CH3:8])[CH:6]=[CH:7][C:2]=1[Cl:1])=[S:11])(=[O:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 14039AcetohydrazideHCID 227520811-Chloro-2-isothiocyanato-4-methylbenzene

Produkt 1

HCID 12207321HCID 12207321, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

One tenth mole, 18.3 g., of 2-chloro-5-methylphenylisothiocyanate and 11.0 g. (0.15 mole) of acetylhydrazine were refluxed for 7 hours in 500 ml. of THF. After cooling, the insoluble product was collected by filtration. The crude product was collected by filtration. The crude product was washed with water, filtered and dried. The yield was 25 g. of 1-acetyl-4-(2-chloro-5-methylphenyl)-3-thiosemicarbazide, m.p. about 145°-157° C.

Aufarbeitung

  1. temperatureAfter cooling
  2. filtrationthe insoluble product was collected by filtration
  3. filtrationThe crude product was collected by filtration
  4. washThe crude product was washed with water
  5. filtrationfiltered
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-f5352f8bef1b41d283c137a3ebfefb54
Quelldatensatz
uspto-grants-1979_01
Patentnummer
US04134914

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