Thionyl Chloride → 6,7-dihydro-5H-dibenzo[a,c]cycloheptene-4-carbonyl chloride

HRID 2164833Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2164833
[CH:1]1[C:6]2[C:7]3[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=3[CH2:9][CH2:10][CH2:11][C:5]=2[C:4]([C:16]([OH:18])=O)=[CH:3][CH:2]=1.S(Cl)([Cl:21])=O>>[CH:1]1[C:6]2[C:7]3[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=3[CH2:9][CH2:10][CH2:11][C:5]=2[C:4]([C:16]([Cl:21])=[O:18])=[CH:3][CH:2]=1

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 132813416,7-dihydro-5H-dibenzo[a,c]cycloheptene-4-carboxylic acid

Produkt 1

HCID 132813426,7-dihydro-5H-dibenzo[a,c]cycloheptene-4-carbonyl chloride

Versuchsvorschrift

Under a dry nitrogen atmosphere a stirred solution of 6,7-dihydro-5H-dibenzo[a,c]cycloheptene-4-carboxylic acid (3.4 grams, 0.0142 mole) in thionyl chloride (10 ml) was heated at reflux for 1.5 hours. The excess thionyl chloride was removed by distillation under reduced pressure. Benzene (10 ml) was added and then removed by distillation under reduced pressure to leave 6,7-dihydro-5H-dibenzo[a,c]cycloheptene-4-carbonyl chloride as a residue.

Aufarbeitung

  1. temperatureat reflux for 1.5 hours
  2. customThe excess thionyl chloride was removed by distillation under reduced pressure
  3. additionBenzene (10 ml) was added
  4. customremoved by distillation under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-1c5790fa1ccc45d495275346f374058b
Quelldatensatz
uspto-grants-1985_03
Patentnummer
US04507317

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