1-[(6-Bromohexyl)oxy]-4-methoxybenzene → 1-[6-(4-Methoxyphenoxy)hexyl]-3-methyl-7-propylxanthine
Reaktionsgleichung
[CH3:1][N:2]1[C:10]2[N:9]=[CH:8][N:7]([CH2:11][CH2:12][CH3:13])[C:6]=2[C:5](=[O:14])[NH:4][C:3]1=[O:15].[CH3:16][O:17][C:18]1[CH:31]=[CH:30][C:21]([O:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]Br)=[CH:20][CH:19]=1>>[CH3:16][O:17][C:18]1[CH:31]=[CH:30][C:21]([O:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][N:4]2[C:5](=[O:14])[C:6]3[N:7]([CH2:11][CH2:12][CH3:13])[CH:8]=[N:9][C:10]=3[N:2]([CH3:1])[C:3]2=[O:15])=[CH:20][CH:19]=1Komponenten
3
Versuchsvorschrift
3-Methyl-7-propylxanthine and 6-(4-methoxyphenoxy)hexyl bromide were reacted and treated in substantially the same manner as described in Example 9 (a) to give 1-[6-(4-methoxyphenoxy)hexyl]-3-methyl-7-propylxanthine (47%).
Aufarbeitung
- additiontreated in substantially the same manner