1-[(6-Bromohexyl)oxy]-4-methoxybenzene → 7-Hexyl-1-[6-(4-methoxyphenoxy)hexyl]-3-methylxanthine
Reaktionsgleichung
[CH2:1]([N:7]1[C:15]2[C:14](=[O:16])[NH:13][C:12](=[O:17])[N:11]([CH3:18])[C:10]=2[N:9]=[CH:8]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH3:19][O:20][C:21]1[CH:34]=[CH:33][C:24]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]Br)=[CH:23][CH:22]=1>>[CH2:1]([N:7]1[C:15]2[C:14](=[O:16])[N:13]([CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][O:25][C:24]3[CH:33]=[CH:34][C:21]([O:20][CH3:19])=[CH:22][CH:23]=3)[C:12](=[O:17])[N:11]([CH3:18])[C:10]=2[N:9]=[CH:8]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]Komponenten
3
Versuchsvorschrift
7-Hexyl-3-Methylxanthine and 6-(4-methoxyphenoxy)hexyl bromide were reacted and treated in substantially the same manner as described in Example 9 (a) to give 7-hexyl-1-[6-(4-methoxyphenoxy)hexyl]-3-methylxanthine (71%) as an oil.
Aufarbeitung
- additiontreated in substantially the same manner