HCID 14405656, Verbindung → HCID 14405658, Verbindung

HRID 2166374Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2166374
[I-].[CH3:2][N+:3]1[CH:8]=[CH:7][C:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])=[CH:5][CH:4]=1>[Pt]=O.CO>[CH3:2][N:3]1[CH2:4][CH2:5][CH:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])[CH2:7][CH2:8]1

Komponenten

4

Edukt 1

HCID 14405656HCID 14405656, Verbindung

Produkt 1

HCID 14405658HCID 14405658, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

4 g (10.5 mmol) of 1-methyl-4-[(1,2,3,4-tetrahydro-2-isoquinolyl)carbonyl]pyridinium iodide and 0.4 g of platinum oxide are introduced into 250 ml of methanol, and the mixture is subjected to hydrogenation for 12 h under a pressure of approximately 0.41 MPa. The catalyst is filtered off, the solvent evaporated off and the residue neutralized, and an oil is obtained which crystallizes and which is used without further treatment in the following stage.

Aufarbeitung

  1. filtrationThe catalyst is filtered off
  2. customthe solvent evaporated off
  3. customthe residue neutralized, and an oil is obtained which
  4. customcrystallizes

Quellen und Nachweise

ORD-Eintrag
ord-8dad04b5717c4364922c72b4f510ed0b
Quelldatensatz
uspto-grants-1990_07
Patentnummer
US04945096

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