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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2166826Erstellt: 26. Oktober 2026

Clonidine → 1H-Imidazol-2-amine, 4,5-dihydro-N-(2,6-dichlorophenyl)-1-(2-quinolinylcarbonyl)-

https://huagongshe.com/reaction/2166826

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktClonidineHCID 2803—
EduktHCID 178519315HCID 178519315—
Produkt1H-Imidazol-2-amine, 4,5-dihydro-N-(2,6-dichlorophenyl)-1-(2-quinolinylcarbonyl)-HCID 306195884,4%

Reaktionsschritte

Using the process described in Example 57, 5.36 g (24 millimoles) of quinolin-2-oyl-imidazolide and 4.6 g (20 millimoles) of 2-(2',6'-dichlorophenylamino)-2-imidazoline give 6.5 g of pure 1-(quinolin-2-oyl)-2-(2',6'-dichlorophenylamino)-2-imidazoline of melting point 193.5°-196° C.; the material is identical with the product obtained according to Example 45.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04389403
Quelldatensatzuspto-grants-1983_06
ORD IDord-65b7fee4ebf4494c86248684c7a4e6ef
Quellennotizuspto-grants-1983_06