HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Clonidine → 1H-Imidazol-2-amine, 4,5-dihydro-N-(2,6-dichlorophenyl)-1-(2-quinolinylcarbonyl)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Clonidine | HCID 2803 | — |
| Edukt | HCID 178519315 | HCID 178519315 | — |
| Produkt | 1H-Imidazol-2-amine, 4,5-dihydro-N-(2,6-dichlorophenyl)-1-(2-quinolinylcarbonyl)- | HCID 3061958 | 84,4% |
Reaktionsschritte
Using the process described in Example 57, 5.36 g (24 millimoles) of quinolin-2-oyl-imidazolide and 4.6 g (20 millimoles) of 2-(2',6'-dichlorophenylamino)-2-imidazoline give 6.5 g of pure 1-(quinolin-2-oyl)-2-(2',6'-dichlorophenylamino)-2-imidazoline of melting point 193.5°-196° C.; the material is identical with the product obtained according to Example 45.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04389403 |
| Quelldatensatz | uspto-grants-1983_06 |
| ORD ID | ord-65b7fee4ebf4494c86248684c7a4e6ef |
| Quellennotiz | uspto-grants-1983_06 |