N'-t-butyl-N'-(3-methylbenzoyl)hydrazine → N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

HRID 21672

Reaktionsgleichung

Reaktionsgleichung von HRID 21672
[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH2:6])([CH3:4])([CH3:3])[CH3:2].[C:16]1([CH:22]([CH:26]([CH3:29])[CH2:27][CH3:28])[C:23](Cl)=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1(C)C=CC=CC=1.[OH-].[Na+]>[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH:6][C:23](=[O:24])[CH:22]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH:26]([CH3:29])[CH2:27][CH3:28])([CH3:4])([CH3:3])[CH3:2]

Komponenten

5

Edukt 2

HCID 15452040N'-t-butyl-N'-(3-methylbenzoyl)hydrazineHCID 218860263-Methyl-2-phenylvaleryl chloride

Produkt 1

HCID 15452019N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14798Sodium HydroxideKatalysatorHCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a stirred suspension of N'-t-butyl-N'-(3-toluoyl)hydrazine (0.7 g) in toluene (10 ml) and aqueous sodium hydroxide (12 drops of 50% aqueous sodium hydroxide) was added dropwise 2-phenyl-3-methyl-pentanoyl chloride (1.0 g). The reaction mixture was stirred overnight, diluted with hexanes and the solids filtered. The solids were washed with hexane and air dried.

Aufarbeitung

  1. filtrationthe solids filtered
  2. washThe solids were washed with hexane and air
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-40b8df1381f7498e92be0080b88467a1
Quelldatensatz
uspto-grants-1995_06
Patentnummer
US05424333

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