Ammonia → Ethyl 4-amino-7-fluoroquinoline-3-carboxylate
Reaktionsgleichung
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[C:13]([O:15][CH2:16][CH3:17])=[O:14].[NH3:18]>>[NH2:18][C:2]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[C:13]([O:15][CH2:16][CH3:17])=[O:14]Komponenten
3
Versuchsvorschrift
Prepared as in Example 1a from ethyl 4-chloro-7-fluoroquinoline-3-carboxylate (Example 9b) and ammonia as an off white solid (99%). MS 235 (MH+).
Quellen und Nachweise
- ORD-Eintrag
- ord-247df5812dd74728abe987d6b0ba8f95
- Quelldatensatz
- uspto-grants-2015_06
- Patentnummer
- US09049878B2
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