2-Methoxyethylamine → (R)-N-(1-(5-bromo-2-((2-methoxyethyl)amino)pyrimidin-4-yl)-2-(3,5-difluorophenyl)ethyl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)acetamide

Reaktionsgleichung

[CH3:1][O:2][CH2:3][CH2:4][NH2:5].[Br:6][C:7]1[C:8]([C@H:17]([NH:27][C:28](=[O:43])[CH2:29][N:30]2[C:38]3[CH2:37][CH2:36][CH2:35][CH2:34][C:33]=3[C:32]([C:39]([F:42])([F:41])[F:40])=[N:31]2)[CH2:18][C:19]2[CH:24]=[C:23]([F:25])[CH:22]=[C:21]([F:26])[CH:20]=2)=[N:9][C:10](S(C)(=O)=O)=[N:11][CH:12]=1>ClCCl>[Br:6][C:7]1[C:8]([C@H:17]([NH:27][C:28](=[O:43])[CH2:29][N:30]2[C:38]3[CH2:37][CH2:36][CH2:35][CH2:34][C:33]=3[C:32]([C:39]([F:42])([F:41])[F:40])=[N:31]2)[CH2:18][C:19]2[CH:24]=[C:23]([F:25])[CH:22]=[C:21]([F:26])[CH:20]=2)=[N:9][C:10]([NH:5][CH2:4][CH2:3][O:2][CH3:1])=[N:11][CH:12]=1