3-(Hydroxymethyl)benzonitrile → 3-(((1,2-Dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)benzonitrile
Reaktionsgleichung
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH3:12])[CH:10]([CH3:13])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[OH:14][CH2:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[C:19]#[N:20]>>[CH3:12][N:11]1[C:4]2[N:5]([C:6](=[O:8])[N:7]=[C:2]([O:14][CH2:15][C:16]3[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=3)[C:19]#[N:20])[CH:3]=2)[CH2:9][CH:10]1[CH3:13]Komponenten
3
Versuchsvorschrift
The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and 3-(hydroxylmethyl)benzonitrile.
Quellen und Nachweise
- ORD-Eintrag
- ord-7214b07fb24b4cdc95af177ecd733a6e
- Quelldatensatz
- uspto-grants-2015_06