4,6-Dichloro-2-methylpyrimidine → 6-chloro-N-((2,4-dimethylthiazol-5-yl)methyl)-2-methylpyrimidin-4-amine
Reaktionsgleichung
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([CH3:9])[N:3]=1.[CH3:10][C:11]1[S:12][C:13]([CH2:17][NH2:18])=[C:14]([CH3:16])[N:15]=1>>[Cl:8][C:6]1[N:5]=[C:4]([CH3:9])[N:3]=[C:2]([NH:18][CH2:17][C:13]2[S:12][C:11]([CH3:10])=[N:15][C:14]=2[CH3:16])[CH:7]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared from 4,6-dichloro-2-methylpyrimidine and (2,4-dimethylthiazol-5-yl)methanamine according to the protocol outlined in Example 1, to afford 3A-1 as a solid. LRMS (ES) (M+H)+: observed=269.1, calculated=269.7.
Aufarbeitung
- customto afford 3A-1 as a solid
Quellen und Nachweise
- ORD-Eintrag
- ord-ccba840ce6df437aa8be4a2dc119943d
- Quelldatensatz
- uspto-grants-2015_06
- Patentnummer
- US09062059B2
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