Sodium Cyanide → 3-Cyanopropyltrivinylsilane

HRID 217568

Reaktionsgleichung

Reaktionsgleichung von HRID 217568
Cl[CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7].[C-:12]#[N:13].[Na+]>CN(C)C=O>[C:12]([CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7])#[N:13]

Komponenten

4

Edukt 2

HCID 8929Sodium CyanideHCID 23630656Trivinyl(3-chloropropyl)silane

Produkt 1

HCID 579456053-CyanopropyltrivinylsilaneAusbeute 86,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

Compound 3-chloropropyltrivinylsilane (1000 mg, 5.35 mmol) and sodium cyanide (525 mg, 10.70 mmol) were dissolved in 18 ml of dimethylformamide, and the mixture was heated at 70° C. for 4 hours. After the reaction, the organic layer was extracted after addition of distilled water and ether, and then purified by column chromatography (n-Hex:EA=10:1, Rf=0.42), to give 818 mg (86% yield) of pure 3-cyanopropyltrivinylsilane.

Aufarbeitung

  1. customAfter the reaction
  2. extractionthe organic layer was extracted
  3. additionafter addition of distilled water and ether
  4. custompurified by column chromatography (n-Hex:EA=10:1, Rf=0.42)

Quellen und Nachweise

ORD-Eintrag
ord-6de4cb8820464af5bd48ac5f26ac22a1
Quelldatensatz
uspto-grants-2012_06
Patentnummer
US08197903B2

Verknüpfte Notizen

Wird geladen…