HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile → 5-(4-Chlorophenyl)-2-hydroxypyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | HCID 2763910 | — |
| Lösungsmittel | Phosphoric Acid | HCID 1004 | — |
| Produkt | 5-(4-Chlorophenyl)-2-hydroxypyridine | HCID 10262372 | 75,6% |
Reaktionsschritte
A mixture of 3-cyano-5-(4-chlorophenyl)-2-pyridinone (4.6 g) and 85% H3PO4 (60 ml) was heated at reflux for 16 hours. The resulting mixture was cooled to room temperature, poured into ice/water and filtered yielding 3.1 g of 5-(4-chlorophenyl)-2-pyridinone as a yellow solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05728715 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-354b2e3cf6af4b84a2f7d3ebed5eb64d |
| Quellennotiz | uspto-grants-1998_03 |