6-(Benzenesulphonylmethyl)-2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)benzoic acid → 2-[2-(t-Butoxycarbonyl)aminoethoxy]-6-(4-fluorobenzenesulphonylmethyl)-3-(furan-3-yl)benzoic acid
Reaktionsgleichung
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([OH:19])=[O:18])=[C:15]([O:20][CH2:21][CH2:22][NH:23][C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[C:14]([C:31]3[CH:35]=[CH:34][O:33][CH:32]=3)=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:36]C1C=CC(C([O-])=O)=C(CS(C2C=CC=CC=2)(=O)=O)C=1C1C=COC=1>>[C:27]([O:26][C:24]([NH:23][CH2:22][CH2:21][O:20][C:15]1[C:14]([C:31]2[CH:35]=[CH:34][O:33][CH:32]=2)=[CH:13][CH:12]=[C:11]([CH2:10][S:7]([C:1]2[CH:2]=[CH:3][C:4]([F:36])=[CH:5][CH:6]=2)(=[O:9])=[O:8])[C:16]=1[C:17]([OH:19])=[O:18])=[O:25])([CH3:29])([CH3:30])[CH3:28]Komponenten
3
Versuchsvorschrift
Prepared by proceeding in a similar manner to Intermediate 6, starting from methyl 2-[2-(t-butoxycarbonyl)aminoethoxy]-6-(4-fluorobenzenesulphonylmethyl-3-(furan-3-yl)benzoate (Intermediate 13).