Sodium Bicarbonate → HCID 69799060, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:31]#[N:32])=[C:6]([CH:30]=1)[O:7][C@@H:8]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][N:14](C(OC(C)(C)C)=O)[CH2:13][CH2:12]1.C(=O)(O)[O-].[Na+]>Cl.O1CCOCC1>[ClH:1].[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:31]#[N:32])=[C:6]([O:7][C@@H:8]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[CH:30]=1Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
The product from step (a) (0.35 g) was stirred in 4M HCl in dioxane (10 ml) for 3 h, then poured into saturated sodium bicarbonate solution (100 ml) and extracted into ethyl acetate. The extract was evaporated to dryness and the residue triturated with 1N HCl in ether to give the product as a white solid.