Methyl morpholine oxide → HCID 22490877, Verbindung
Reaktionsgleichung
[F:1]/[C:2](=[C:5](/[C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][C:16]=1[O:17][CH2:18][CH2:19][CH3:20])[O:13][C:12]([CH3:22])([CH3:21])[CH:11]=[C:10]2[CH:23]([CH3:25])[CH3:24])\[CH3:6])/[CH2:3][OH:4].C[N+]1([O-])CCOCC1>>[F:1]/[C:2](=[C:5](/[C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][C:16]=1[O:17][CH2:18][CH2:19][CH3:20])[O:13][C:12]([CH3:22])([CH3:21])[CH:11]=[C:10]2[CH:23]([CH3:24])[CH3:25])\[CH3:6])/[CH:3]=[O:4]Komponenten
3
Versuchsvorschrift
Following General Procedure M, (2E)-2-fluoro-3-(4-isopropyl-2,2-dimethyl-7-propoxy-2H-chromen-6-yl)-but-2-en-1-ol (Compound 86, 100 mg, 0.27 mmol) and 4-methylmorpholine N-oxide (75 mg, 0.57 mmol) were reacted to give the title compound as a yellow oil.
Aufarbeitung
- customwere reacted
Quellen und Nachweise
- ORD-Eintrag
- ord-d6d6869a68dd42e9a53903353c296ce4
- Quelldatensatz
- uspto-grants-2005_05