N-(Phenylacetyl)-L-alanine → HCID 22895054, Verbindung
Reaktionsgleichung
[C:1]1([CH2:7][C:8]([NH:10][C@H:11]([C:13]([OH:15])=O)[CH3:12])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[CH3:17][O:18][C:19](=[O:34])[C@H:20]([CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])[NH:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23]>>[CH3:17][O:18][C:19](=[O:34])[C@H:20]([CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])[N:21]([C:13](=[O:15])[C@H:11]([CH3:12])[NH:10][C:8](=[O:9])[CH2:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:22]([O:24][C:25]([CH3:28])([CH3:26])[CH3:27])=[O:23]Komponenten
3
Versuchsvorschrift
Following General Procedure A and using N-(phenylacetyl)-L-alanine (from Example B1 above) and N,-(tert-butoxycarbonyl)-L-lysine methyl ester hydrochloride (Bachem), the title compound was prepared as a solid (mp=119-121° C.). The reaction was monitored by tlc (Rf=0.46 in 90:10:1 CH2Cl2MeOHNH4OH).
Quellen und Nachweise
- ORD-Eintrag
- ord-d0a4f973fa7644cd8b3d95694f8749e8
- Quelldatensatz
- uspto-grants-2005_05