HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloromethyl-2-(4-isopropyl-phenyl)-thiazole → Rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1h-indol-6-yl}-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloromethyl-2-(4-isopropyl-phenyl)-thiazole | HCID 2095697 | — |
| Edukt | Rac-2-ethoxy-3-(1h-indol-6-yl)-propionic acid ethyl ester | HCID 69563615 | — |
| Produkt | Rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1h-indol-6-yl}-propionic acid | HCID 10456332 | — |
Reaktionsschritte
In analogy to the procedure described in example 44, rac-2-ethoxy-3-(1H-indol-6-yl)-propionic acid ethyl ester (preparation 11) was reacted with 4-chloromethyl-2-(4-isopropyl-phenyl)-thiazole to give rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1H-indol-6-yl}-propionic acid as yellow viscous oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06890947B2 |
| Quelldatensatz | uspto-grants-2005_05 |
| ORD ID | ord-6b99233aa2be4d6781dd193b809309ec |
| Quellennotiz | uspto-grants-2005_05 |