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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2183702Erstellt: 24. Oktober 2026

3-Cyclohexylimidazo[1,5-a]pyrazine → 3-cyclohexyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazine

https://huagongshe.com/de/reaction/2183702

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Cyclohexylimidazo[1,5-a]pyrazineHCID 21983665—
EduktHCID 178418361HCID 178418361—
KatalysatorAdams' catalystHCID 345198—
LösungsmittelEthanolHCID 702—
Produkt3-cyclohexyl-5H,6H,7H,8H-imidazo[1,5-a]pyrazineHCID 2198360887,5%

Reaktionsschritte

A solution of 3-cyclohexyl-imidazo[1,5-a]pyrazine 8a (960 mg, 4.4 mmol) in 25 ml ethanol was treated with 100 mg Adam's catalyst and stirred vigorously under one atmosphere of hydrogen for 18 hr. The mixture was filtered through a pad of Celite®. The filtrate was concentrated in vacuo to yield 790 mg of 3-cyclohexyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine 9a as a greenish-yellow solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06900220B2
Quelldatensatzuspto-grants-2005_05
ORD IDord-b160e3c02ae6415d9a8fb16a78205e97
Quellennotizuspto-grants-2005_05