Npc164440 → N-(cis-5,8,11,14,17-Eicosapentaenoyl)-O-Phospho-2-Aminoethanol

HRID 2185850

Reaktionsgleichung

Reaktionsgleichung von HRID 2185850
[C:1]([NH:22][CH2:23][CH2:24][O:25][P:26](=[O:28])=[O:27])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7][CH:8]=[CH:9][CH2:10][CH:11]=[CH:12][CH2:13][CH:14]=[CH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C(O)(=O)CCC/C=C\CC=CCC=CCC=CCC=CCC>>[C:1]([NH:22][CH2:23][CH2:24][O:25][P:26](=[O:28])=[O:27])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7][CH:8]=[CH:9][CH2:10][CH:11]=[CH:12][CH2:13][CH:14]=[CH:15][CH2:16][CH:17]=[CH:18][CH2:19][CH3:20]

Komponenten

3

Edukt 2

HCID 70198906Npc164440HCID 86583926N-(cis-5,8,11,14-Eicosatetraenoyl)-O-Phospho-2-Aminoethanol

Produkt 1

HCID 86583933N-(cis-5,8,11,14,17-Eicosapentaenoyl)-O-Phospho-2-Aminoethanol

Versuchsvorschrift

This compound was prepared as described above for (5) using 0.5 mmol (151 mg) of cis-5,8,11,14,17-eicosapentaenoic acid; yield 98 mg, (46%); Rf 0.10-0.15 (system B); 1H-NMR (CD3SOCD3, 200 MHz) δ0.9-1.0 (t, 3H, ω-CH3); 1.5-1.6 (t, 2H, CH2); 2.0-2.2 (m, 6H, CH2CO and 2CH2CH═CH); 2.7-2.9 (br s, 8H, 4HC═CH—CH2—CH═CH); 3.2-3.3 (br s, 2H, CH2NH); 3.8-3.9 (br s, 2H, CH2OP); 5.2-5.4 (br s, 10H, 5 HC═CH); 8.2-8.4 (m, 3H, NH and 2POH)

Aufarbeitung

  1. customThis compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-ec7134caa0194f478ea6cd3a4e277504
Quelldatensatz
uspto-grants-2002_06
Patentnummer
US06403554B2

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