4-(2-(Methylsulfonyl)phenyl)piperidine → N-[2-(3,4-Difluorophenyl)-4-[4-[2-methylsulfonylphenyl]-1-piperidinyl]butyl]-N-methyl-5,6,7,8-tetrahydro-1-naphthamide

Beteiligte Stoffe

Reaktionsschritte

Using standard reductive amination conditions N-[2-(3,4-difluorophenyl)-4-oxobutyl]-N-methyl-5,6,7,8-tetrahydro-1-naphthamide was reacted with 4-[2-methylsulfonylphenyl]piperidine and converted to the citrate salt. MS: m/z 595 (M+H). Analysis for C34H40F2N2O3S.C6H8O7.1.4 H2O: calculated: C, 59.16; H, 6.31; N, 3.45; found: C, 59.04; H, 6.10; N, 4.08.

Herkunft & Nachweise