Hydrogen Bromide → 1-Bromo-1-(3,4-dimethoxyphenyl)ethene
Reaktionsgleichung
[BrH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([C:12]#[CH:13])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>>[Br:1][C:12]([C:6]1[CH:7]=[CH:8][C:9]([O:10][CH3:11])=[C:4]([O:3][CH3:2])[CH:5]=1)=[CH2:13]Komponenten
3
Versuchsvorschrift
According to the General Procedure D, HBr (33% in acetic acid, 1.11 ml, 0.50 g, 6.17 mmol) and 3,4-di-methoxyphenylacetylene (1.00 g, 6.17 mmol) are converted to give after workup and chromatography (SiO2, PE/EE 5:1, Rf=0.41) the title compound (1.30 g, 5.35 mmol, 87%) as a brown oil; C10H11BrO2 (243.10).
Quellen und Nachweise
- ORD-Eintrag
- ord-621fff9adae0444882c64c63d52d9e83
- Quelldatensatz
- uspto-grants-2012_12
- Patentnummer
- US08324404B2
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