4-Methylpyridine → 1,1'-{Disulphanediylbis[ethane-2,1-diylimino(2-oxoethane-2,1-diyl)]}bis(4-methylpyridinium)dichloride

HRID 2191177

Reaktionsgleichung

Reaktionsgleichung von HRID 2191177
[S:1]([CH2:10][CH2:11][NH:12][C:13](=[O:16])[CH2:14]Cl)[S:2][CH2:3][CH2:4][NH:5][C:6](=[O:9])[CH2:7][Cl:8].[N:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1>CN1C(=O)CCC1>[Cl-:8].[Cl-:8].[S:1]([CH2:10][CH2:11][NH:12][C:13](=[O:16])[CH2:14][N+:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1)[S:2][CH2:3][CH2:4][NH:5][C:6](=[O:9])[CH2:7][N+:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1

Komponenten

4

Edukt 2

HCID 79634-MethylpyridineHCID 20525005N,N'-(disulfanediyldiethane-2,1-diyl)bis(2-chloroacetamide)

Produkt 1

HCID 866322821,1'-{Disulphanediylbis[ethane-2,1-diylimino(2-oxoethane-2,1-diyl)]}bis(4-methylpyridinium)dichloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 13387N-methyl-2-pyrrolidoneLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

6.1 g of N,N′-(disulphanediyldiethane-2,1-diyl)bis(2-chloroacetamide) and 4.5 g of 4-picoline are dissolved in 50 ml of NMP and the solution is heated at 80° C. for 19 hours. After the mixture has been cooled, 9.2 g of salts are recovered by successive precipitations from acetone and drying under vacuum. The analyses show that the product conforms. 1H NMR (400 MHz, D2O): 2.61 (s, 6H), 2.82 (t, 4H), 3.56 (t, 4H), 5.31 (s, 4H), 7.85 (d, 4H), 8.51 (d, 4H).

Aufarbeitung

  1. temperatureAfter the mixture has been cooled
  2. custom9.2 g of salts are recovered by successive precipitations from acetone
  3. customdrying under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-4fa68b74b4be4644932bba6cad8a6cc5
Quelldatensatz
uspto-grants-2012_12
Patentnummer
US08328880B2

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