HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Isocyanatothiophene → 1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Isocyanatothiophene | HCID 2776375 | — |
| Edukt | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Produkt | 1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 58329396 | 48,3% |
Reaktionsschritte
1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione (19 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.10 mmol) and 2-isocyanatothiophene (0.4 mmol) following general procedure C. LCMS: m/z 394 [M+1]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08329715B2 |
| Quelldatensatz | uspto-grants-2012_12 |
| ORD ID | ord-a7f6c04a8f8c479ebca0fd83aaecf77c |
| Quellennotiz | uspto-grants-2012_12 |