4-(4-Chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazole → 3-{9-[3-methoxy-4-((5-methyl-2-(thiophene-2-yl)-oxazole-4-yl)methoxy)-benzyl]-9H-carbazole-4-yloxy}-2,2-dimethyl-propionic acid

HRID 2194303

Reaktionsgleichung

Reaktionsgleichung von HRID 2194303
[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[C:4]([O:14][CH2:15][C:16]([CH3:21])([CH3:20])[C:17]([OH:19])=[O:18])=[CH:3][CH:2]=1.C1C2NC3C(=CC=CC=3)C=2C(OC(C)(C)C(O)=O)=CC=1.Cl[CH2:43][C:44]1[CH:62]=[CH:61][C:47]([O:48][CH2:49][C:50]2[N:51]=[C:52]([C:56]3[S:57][CH:58]=[CH:59][CH:60]=3)[O:53][C:54]=2[CH3:55])=[C:46]([O:63][CH3:64])[CH:45]=1.ClCC1C=CC(OCC2N=C(C3C=CC=CC=3)OC=2C)=C(OC)C=1>>[CH3:64][O:63][C:46]1[CH:45]=[C:44]([CH:62]=[CH:61][C:47]=1[O:48][CH2:49][C:50]1[N:51]=[C:52]([C:56]2[S:57][CH:58]=[CH:59][CH:60]=2)[O:53][C:54]=1[CH3:55])[CH2:43][N:12]1[C:13]2[CH:1]=[CH:2][CH:3]=[C:4]([O:14][CH2:15][C:16]([CH3:21])([CH3:20])[C:17]([OH:19])=[O:18])[C:5]=2[C:6]2[C:11]1=[CH:10][CH:9]=[CH:8][CH:7]=2

Komponenten

5

Edukt 4

HCID 223446094-(4-Chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazoleHCID 595717393-(9H-carbazole-4-yloxy)-2,2-dimethylpropionic acidHCID 595717422-(9H-carbazole-4-yloxy)-2-methylpropionic acidHCID 595717574-((4-(Chloromethyl)-2-methoxyphenoxy)methyl)-2-(thiophene-2-yl)-5-methyloxazole

Produkt 1

HCID 116357183-{9-[3-methoxy-4-((5-methyl-2-(thiophene-2-yl)-oxazole-4-yl)methoxy)-benzyl]-9H-carbazole-4-yloxy}-2,2-dimethyl-propionic acid

Versuchsvorschrift

The subject compound was prepared by performing the same operation as that of the example 3 by using 3-(9H-carbazole-4-yloxy)-2,2-dimethylpropionic acid prepared by the reference 30 instead of 2-(9H-carbazole-4-yloxy)-2-methylpropionic acid used in the example 3, and using 4-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-2-(thiophene-2-yl)-5-methyloxazole prepared by the reference 3 instead of 4-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-5-methyl-2-phenyloxazole.

Aufarbeitung

  1. customThe subject compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-67ab8348654d4b7f896506ecc8e62622
Quelldatensatz
uspto-grants-2012_12
Patentnummer
US08329913B2

Verknüpfte Notizen

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