3-Methylphenylacetylene → 2-(2-methoxy-ethyl)-5-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-2H-pyridazin-3-one
Reaktionsgleichung
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[C:10](=[O:11])[CH:9]=[C:8]([N:12]2[CH:16]=[C:15](I)[N:14]=[C:13]2[CH3:18])[CH:7]=[N:6]1.[C:19]([C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([CH3:27])[CH:22]=1)#[CH:20]>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[C:10](=[O:11])[CH:9]=[C:8]([N:12]2[CH:16]=[C:15]([C:20]#[C:19][C:21]3[CH:22]=[C:23]([CH3:27])[CH:24]=[CH:25][CH:26]=3)[N:14]=[C:13]2[CH3:18])[CH:7]=[N:6]1Komponenten
3
Versuchsvorschrift
The title compound, light yellow viscous oil, MS: m/e=349.4 (M+H+), was prepared in accordance with the general method of example 21a from 2-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one and 1-ethynyl-3-methyl-benzene.
Quellen und Nachweise
- ORD-Eintrag
- ord-34109f25506044dd9acfd6c3a436a872
- Quelldatensatz
- uspto-grants-2012_12
- DOI