HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosphoric Acid → Tamiflu
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosphoric Acid | HCID 1004 | — |
| Edukt | Oseltamivir | HCID 65028 | — |
| Produkt | Tamiflu | HCID 78000 | — |
Reaktionsschritte
Form B may be formed by adding (3R,4R,5S)-4-acetylamino-5-amino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester to the phosphoric acid and cooling the supersaturated solution from 50° C. to −40° C. as fast as possible (without seeding).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08334319B2 |
| Quelldatensatz | uspto-grants-2012_12 |
| ORD ID | ord-0c10069f60fc4ba9a6e569cad3915ad6 |
| Quellennotiz | uspto-grants-2012_12 |