HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Hydroxypyrrolidine → 1-[3-Fluoro-2-(trifluoromethyl)phenyl]pyrrolidin-3-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Hydroxypyrrolidine | HCID 98210 | — |
| Edukt | 2-Bromo-6-fluorobenzotrifluoride | HCID 2773345 | — |
| Produkt | 1-[3-Fluoro-2-(trifluoromethyl)phenyl]pyrrolidin-3-ol | HCID 67022262 | 24% |
Reaktionsschritte
The title compound (6.2 g, yield 24%) was obtained from 1-bromo-3-fluoro-2-(trifluoromethyl)benzene and 3-hydroxypyrrolidine by a method similar to that in Reference Example 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08338622B2 |
| Quelldatensatz | uspto-grants-2012_12 |
| ORD ID | ord-b57590e32b9e42eaad5d61f2b2c47f96 |
| Quellennotiz | uspto-grants-2012_12 |