Hydrochloric Acid → 1-(6'-Methoxy-1-naphthoxy)-3-(iso-propylamino)-2-propanol hydrochloride

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 9.5 parts of 6-methoxy-1-naphthol, 5.8 parts of 1-(iso-propyl)-3-azetidinol and 0.3 part of potassium hydroxide was heated under nitrogen gas at 140° C. for 8 hours with agitation. The reaction mixture was treated in the same manner as in Example 1, and when the resulting hydrochloride was recrystallized from iso-propyl alcohol, there was obtained 17.7 parts of 1-(6'-methoxy-1-naphthoxy)-3-(iso-propylamino)-2-propanol hydrochloride melting at 165°-167° C. The yield was 57.5%.

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