Benzyl Bromide → Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

HRID 2200390Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2200390
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].C(=O)([O-])[O-].[K+].[K+].[CH2:20](Br)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>CC(C)=O>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[O:8][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Komponenten

5

Edukt 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 10634081Methyl 2-(3-bromo-4-hydroxyphenyl)acetate

Produkt 1

HCID 56605342Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

Compound 10 (12.3 g) was dissolved in 100 mL acetone and 7.6 g of potassium carbonate was added. 8.6 g of benzyl bromide was added with stirring. The solid was removed by suction filtration and the liquid was evaporated to product 11.

Aufarbeitung

  1. customThe solid was removed by suction filtration
  2. customthe liquid was evaporated to product 11

Quellen und Nachweise

ORD-Eintrag
ord-d183db3ee6454f69b0c850e9b2968b79
Quelldatensatz
uspto-grants-2016_06
Patentnummer
US09359372B2

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