Chloroacetone → HCID 90402786, Verbindung
Reaktionsgleichung
[C:1]([CH2:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([NH2:9])=[O:8])#[N:2].Cl[CH2:14][C:15](=O)[CH3:16]>>[CH3:16][C:15]1[N:9]=[C:7]([C:6]2[CH:5]=[C:4]([CH2:3][C:1]#[N:2])[CH:12]=[CH:11][CH:10]=2)[O:8][CH:14]=1Komponenten
3
Versuchsvorschrift
A solution of 3-(cyanomethyl)benzamide (200 mg, 1.25 mmol) in 1-chloropropan-2-one (2 mL) was microwave irradiated at 120 for 20 min in a sealed tube. The mixture was concentrated to give crude product (110 mg), which was directly used to the next reaction without purification. LCMS MH+ 199.
Aufarbeitung
- concentrationThe mixture was concentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-a67079d97cd44a5fa76841c3a5d6db89
- Quelldatensatz
- uspto-grants-2016_06
- Patentnummer
- US09359359B2
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